Manny Machado homered and Chris Paddack limited Arizona to three hits over 5 1/3 innings, leading the San Diego Padres to a 2-1 win over the Diamondbacks on Friday night.

In addition to his home run, Machado made a fine defensive play on a sharp grounder up the third base line late in the game. Fernando Tatis doubled, knocking in the go-ahead run in the seventh inning, and San Diego won its third straight and fourth in five games.

Paddack (1-0) allowed one run and struck out five. Gerardo Reyes, called up earlier in the day, earned the win in his major league debut by getting two outs in the sixth inning.

Arizona Diamondbacks starting pitcher Luke Weaver throws to a San Diego Padres batter during the first inning of a baseball game Friday, April 12, 2019, in Phoenix. (AP Photo/Matt York)
Arizona Diamondbacks starting pitcher Luke Weaver throws to a San Diego Padres batter during the first inning of a baseball game Friday, April 12, 2019, in Phoenix. (AP Photo/Matt York)

Three Padres relievers held the Diamondbacks hitless over 3 2/3 innings, including Kirby Yates’ scoreless ninth for his National League-leading eighth save.

Arizona has lost three in a row and four of five.

Luke Weaver (0-1) retired nine straight from the fourth to the seventh inning before giving up back-to-back, one-out doubles to Wil Myers and Tatis. Myers scored as Tatis just missed a home run, his drive hitting the base of the right field fence.

San Diego Padres starting pitcher Chris Paddack throws to an Arizona Diamondbacks batter during the first inning of a baseball game Friday, April 12, 2019, in Phoenix. (AP Photo/Matt York)
San Diego Padres starting pitcher Chris Paddack throws to an Arizona Diamondbacks batter during the first inning of a baseball game Friday, April 12, 2019, in Phoenix. (AP Photo/Matt York)

Weaver lasted 6 1/3 innings and allowed two runs on five hits, with eight strikeouts and two walks. The Diamondbacks also got scoreless relief from three pitchers.

Machado homered to the opposite field, into the right-field seats, on a 2-2 pitch. It was his fourth home run of the season.

Jarrod Dyson’s hustle helped the Diamondbacks tie the game in the third. He made it to second base for a one-out hustle double, and scored on David Peralta’s two-out single.

San Diego Padres shortstop Fernando Tatis Jr. dives under the tag by Arizona Diamondbacks first baseman Wilmer Flores, left, to get back to first base safely during the eighth inning of a baseball game Thursday, April 11, 2019, in Phoenix. (AP Photo/Ross D. Franklin)
San Diego Padres shortstop Fernando Tatis Jr. dives under the tag by Arizona Diamondbacks first baseman Wilmer Flores, left, to get back to first base safely during the eighth inning of a baseball game Thursday, April 11, 2019, in Phoenix. (AP Photo/Ross D. Franklin)

PITCHER MOVES

Right-hander Pedro Avila, who started Thursday night’s game for San Diego, was optioned to Double-A Amarillo on Friday. Right-hander Reyes was brought up from Triple-A El Paso.

CUP TOUR

San Diego Padres' Manny Machado celebrates his solo home run with Padres' Franmil Reyes (32) against the Arizona Diamondbacks during the first inning of a baseball game Friday, April 12, 2019, in Phoenix. (AP Photo/Matt York)
San Diego Padres’ Manny Machado celebrates his solo home run with Padres’ Franmil Reyes (32) against the Arizona Diamondbacks during the first inning of a baseball game Friday, April 12, 2019, in Phoenix. (AP Photo/Matt York)

The CONCACAF Gold Cup trophy made its way to Chase Field on Friday night to promote the upcoming North American soccer championship tournament that will predominantly be played in U.S. venues in June and July. One of those stadiums is nearby State Farm Stadium, which will host a semifinal match on July 2.

TRAINER’S ROOM

Diamondbacks: RHP Taijuan Walker threw a bullpen session Friday in his rehabilitation from Tommy John surgery almost a year ago.

Arizona Diamondbacks' David Peralta follows through on an RBI base hit during the third inning of the team's baseball game against the San Diego Padres, Friday, April 12, 2019, in Phoenix. (AP Photo/Matt York)
Arizona Diamondbacks’ David Peralta follows through on an RBI base hit during the third inning of the team’s baseball game against the San Diego Padres, Friday, April 12, 2019, in Phoenix. (AP Photo/Matt York)

UP NEXT

LHP Matt Strahm (0-2, 7.04 earned run average) is scheduled to start for the Padres in the third game of their series. Arizona counters with RHP Merrill Kelly (1-1, 2.57).

___

San Diego Padres' Manny Machado looks to the mound after striking out against the Arizona Diamondbacks during the sixth inning of a baseball game, Friday, April 12, 2019, in Phoenix. (AP Photo/Matt York)
San Diego Padres’ Manny Machado looks to the mound after striking out against the Arizona Diamondbacks during the sixth inning of a baseball game, Friday, April 12, 2019, in Phoenix. (AP Photo/Matt York)
Arizona Diamondbacks' Jarrod Dyson scores on a base hit by David Peralta during the third inning of a baseball game against the San Diego Padres on Friday, April 12, 2019, in Phoenix. (AP Photo/Matt York)
Arizona Diamondbacks’ Jarrod Dyson scores on a base hit by David Peralta during the third inning of a baseball game against the San Diego Padres on Friday, April 12, 2019, in Phoenix. (AP Photo/Matt York)
San Diego Padres Wil Myers (4) high-fives teammates after scoring against the Arizona Diamondbacks during the seventh inning of a baseball game Friday, April 12, 2019, in Phoenix. (AP Photo/Matt York)
San Diego Padres Wil Myers (4) high-fives teammates after scoring against the Arizona Diamondbacks during the seventh inning of a baseball game Friday, April 12, 2019, in Phoenix. (AP Photo/Matt York)
Arizona Diamondbacks relief pitcher Yoshihisa Hirano throws to a San Diego Padres batter during the seventh inning of a baseball game Friday, April 12, 2019, in Phoenix. (AP Photo/Matt York)
Arizona Diamondbacks relief pitcher Yoshihisa Hirano throws to a San Diego Padres batter during the seventh inning of a baseball game Friday, April 12, 2019, in Phoenix. (AP Photo/Matt York)

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