Nelson Cruz hit two of the Minnesota Twins’ five home runs off Baltimore in a 6-1 win over the Orioles on Friday night.

Cruz, Eddie Rosario and C.J. Cron hit consecutive home runs in the first inning off Alex Cobb (0-2), with Cruz and Rosario connecting on back-to-back pitches. Max Kepler homered off Cobb in the fourth, and Cruz homered against Gabriel Ynoa in the fifth.

Baltimore has allowed 64 home runs in 27 games — no other major league team had given up more than 46 entering Friday.

Minnesota Twins' Nelson Cruz, left, celebrates his solo home run off Baltimore Orioles' pitcher Alex Cobb as he passes Orioles catcher Jesus Sucre in the first inning of a baseball game Friday, April 26, 2019, in Minneapolis. (AP Photo/Jim Mone)
Minnesota Twins’ Nelson Cruz, left, celebrates his solo home run off Baltimore Orioles’ pitcher Alex Cobb as he passes Orioles catcher Jesus Sucre in the first inning of a baseball game Friday, April 26, 2019, in Minneapolis. (AP Photo/Jim Mone)

Cruz had his second multihomer game this season after going deep twice last weekend in Cobb’s previous start. Minnesota scored 26 runs and hit 11 homers — three off Cobb — in a three-game sweep at Baltimore last weekend.

Rosario has 11 homers, all since April 6, and 22 RBIs in his last 17 games.

Martin Perez (3-0) gave up one run and six hits in six innings.

Minnesota Twins' C.J. Cron, left, rounds the bases on a solo home run off Baltimore Orioles' pitcher Alex Cobb in the first inning of a baseball game Friday, April 26, 2019, in Minneapolis. (AP Photo/Jim Mone)
Minnesota Twins’ C.J. Cron, left, rounds the bases on a solo home run off Baltimore Orioles’ pitcher Alex Cobb in the first inning of a baseball game Friday, April 26, 2019, in Minneapolis. (AP Photo/Jim Mone)

Cobb allowed five runs — four earned — and six hits in four innings.

Dwight Smith Jr. singled in a run for Baltimore in the sixth.

Trey Mancini had three hits for Baltimore. Mancini has hit safely in eight straight games and entered the day leading the AL in hits.

Baltimore Orioles catcher Jesus Sucre, left, visits at the mound with pitcher Alex Cobb after Cobb gave up three solo home runs in a row by the Minnesota Twins in the first inning of a baseball game Friday, April 26, 2019, in Minneapolis. (AP Photo/Jim Mone)
Baltimore Orioles catcher Jesus Sucre, left, visits at the mound with pitcher Alex Cobb after Cobb gave up three solo home runs in a row by the Minnesota Twins in the first inning of a baseball game Friday, April 26, 2019, in Minneapolis. (AP Photo/Jim Mone)

TRAINER’S ROOM

Twins: RHP Matt Magill (right shoulder tendinitis) was activated from the injured list. Minnesota sent RHP Chase De Jong outright to Triple-A Rochester. … Manager Rocco Baldelli said Miguel Sano (cut right heel) homered in an extended spring training game. Baldelli said Sano is not yet ready to begin a rehab assignment.

UP NEXT

Baltimore Orioles pitcher Alex Cobb looks down at the mound after giving up a solo home run to Minnesota Twins' Max Kepler in the fourth inning of a baseball game Friday, April 26, 2019, in Minneapolis. (AP Photo/Jim Mone)
Baltimore Orioles pitcher Alex Cobb looks down at the mound after giving up a solo home run to Minnesota Twins’ Max Kepler in the fourth inning of a baseball game Friday, April 26, 2019, in Minneapolis. (AP Photo/Jim Mone)

Following an extra day of rest, RHP Jose Berrios (3-1, 2.97 ERA) starts Saturday against the Orioles, who counter with RHP Dan Straily (1-1, 8.59). Berrios gave up a season-high four runs in six innings at Baltimore on April 20. Straily opposed Berrios in that last outing, yielding three runs in five innings.

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